- Alphonso Davies (VAN)
- Tyler Adams (RBNY)
- Diego Rossi (LAFC)
- Yangel Herrera (NYC)
- Jefferson Savarino (RSL)
- Ezequiel Barco (ATL)
- Reggie Cannon (DAL)
- Jesus Medina (NYC)
- Justen Glad (RSL)
- Auston Trusty (PHI)
- Latif Blessing (LAFC)
- Milton Valenzuela (CLB)
- Andre Horta (LAFC)
- Chris Durkin (DC)
- Brooks Lennon (RSL)
- Eduard Atuesta (LAFC)
- Efrain Alvarez (LA)
- Pablo Aranguiz (DAL)
- Andrew Carleton (ATL)
- Jaylin Lindsey (SKC)
- Mark McKenzie (PHI)
- Derrick Jones (PHI)
2018 22 Under 22 Rankings

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