Atlanta will clinch a berth in the Audi 2021 MLS Cup Playoffs IF:
- Atlanta win or tie vs. Cincinnati
or:
- New York lose vs. Nashville
or:
- Montréal lose or tie vs. Orlando
or:
- Atlanta win goal differential vs. Orlando
Atlanta will clinch a top-four seed in Eastern Conference IF:
- Atlanta win vs. Cincinnati AND
- New York City lose vs. Philadelphia AND
- Orlando lose or tie vs. Montréal
or:
- Atlanta win vs. Cincinnati AND
- New York City lose vs. Philadelphia AND
- Atlanta win goal differential vs. Orlando