Vancouver will clinch a berth in the Audi 2021 MLS Cup Playoffs IF:
- Vancouver win or tie vs. Seattle
or:
- LA lose vs. Minnesota AND
- Salt Lake lose or tie vs. Kansas City
or:
- LA lose vs. Minnesota AND
- LAFC lose or tie vs. Colorado
or:
- Salt Lake lose or tie vs. Kansas City AND
- LAFC lose or tie vs. Colorado